Pandora Internet Radio is very, very cool. You tell it a song or artist you like, and it creates a "radio station" with a playlist full of songs that it thinks you will also like. As it plays songs, you can give them a thumbs up or thumbs down, and the playlist is adjusted accordingly.
I created one radio station based on the band Moxy Fruvous, another based on the song "John Lee Supertaster" by They Might Be Giants plus the band Supertramp (that one was interesting), and a third based on "Honey Bee" by Tom Petty.
Have fun. (h/t Defective Yeti)
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